Gastric Ulcers and the Off-Track Thoroughbred

By Dr. Bill Vandergrift, EquiVision, Inc. Download PDF

Current estimates indicate that approximately 80% of Thoroughbreds retiring from racing suffer from gastric ulcers ranging from mild to severe. To understand how to help your off-track Thoroughbred (OTTB) recover from gastric ulcers, it is helpful to understand why gastric ulcers are so prevalent in race horses.

Causes: The primary risk factors for gastric ulceration in race horses include intense exercise, eating large amounts of grain, eating on an irregular schedule, stall confinement, administration of drugs such as non-steroidal, anti-inflammatory drugs (NSAIDs), exposure to pathogenic bacteria and viruses, and increased emotional and physical stress.

Race exercise increases the production of gastric acid by increasing the production of hormones responsible for stimulating acid production in the stomach. Race exercise also increases exposure of the increased amounts of acid to the non-glandular areas of the stomach and esophagus due to the splash effect caused by intense physical activity in the horse. It is easy to understand how these two factors combine to increase inflammation and ulceration of the stomach. The consumption of large amounts of grain (oats, barley, corn, etc.) often leads to increased production of volatile fatty acids in the stomach. Increased production of volatile fatty acids in the stomach contributes to a drop in pH of stomach contents, which in turn contributes to increased inflammation and ulceration of gastric tissues. Race horses that do not have constant access to food are particularly susceptible to gastric ulcers. Horses are designed to be constant grazers and have a small amount of food flowing through their stomach on a consistent basis. When a horse does not have access to food, the stomach pretty much empties in approximately one hour. Unfortunately for the horse, especially high performance horses like race horses, acid production and secretion does not stop just because the stomach is empty. An empty stomach exposed to acid secretion on a day-in, day-out basis is an ulcer just looking for a place to happen. Epidemiological studies have found that horses kept in stalls for prolonged periods of time are more susceptible to all kinds of gastro-intestinal disorders such as colic, gastric ulcers and intestinal inflammation. In addition to being designed to be constant grazers, horses are designed to move about freely and regularly. Free exercise enhances digestion whilst intense exercise, or lack of adequate exercise, interferes with normal function of the digestive system. It is well known that NSAIDs increase gastric ulceration in people as well as horses. Many race horses receive phenylbutazone or banamine on a regular basis. The ability of NSAIDs to produce gastric ulcers in individual horses varies. Some horses are very susceptible to gastric ulcers when given phenylbutazone, for example, while the horse in the stall right next door may be able to tolerate much greater and more frequent doses with no apparent ill effects. Since we really cannot tell what an individual horse’s tolerance level to certain NSAIDs is, it is a good practice to use these drugs only on an as-needed basis and as conservatively as possible to obtain the desired therapeutic effect. The jury is still out on the prevalence of gastric ulcers in horses caused by pathogenic bacteria like Helicobacter spp. and possibly other pathogenic organisms. However, it is believed that once gastric ulcers are present in the horse, opportunistic bacteria such as E. coli may inhibit the healing of gastric ulcers. Bacterial involvement in gastric ulcers should be considered when normal treatments for gastric ulcers do not appear to be effective. In such cases, antibiotic treatment may be warranted, but should be done under a veterinarian’s supervision. Race horses are subjected to various emotional stress factors while in training and actively racing; horses are not that unlike people in this regard. Some horses will display emotional stress outwardly by becoming very reactive, while others appear stoic and tend to internalize their emotions, and the remainder just seem to go with the flow and take everything in stride. Horses that internalize their stress are just as susceptible, if not more so, to developing gastric ulcers as individuals who are more expressive and tend to become hyper-reactive. Racing is physically demanding and comes with its fair share of aches and pains, as is the case with any athletic endeavor, human or equine. Physical stress (pain) increases the chances of horses developing gastric ulcers. In these cases, successful treatment of gastric ulcers will include alleviating physical pain as well.

How to know if your OTTB has gastric ulcers?

If you are working with an off-track Thoroughbred that has been recently retired from racing, you are safe to assume that your horses has gastric ulcers to one degree or another. The only sure way to diagnose gastric ulcers is gastroscopy. However, observing and taking note of certain behaviors consistent with gastric ulcers in horses is extremely useful as well. Sometimes treating the horse with omeprazole and noting improvements in attitude, appetite and/or condition can be considered a positive diagnosis for gastric ulcers in an individual horse. Horses with gastric ulcers may present with one or more of the following symptoms: poor appetite, display of colic symptoms during or shortly after eating a grain meal, poor hair coat quality, low body condition score, loose manure, off-smell to manure, bad breath, snarky attitude, over-reaction to normal stimuli, resistant to being groomed, and non-compliance under saddle. Obviously these symptoms are not unique to gastric ulcers, but gastric ulcers should be considered if more than one of these symptoms is presented concurrently.

Treatment and prevention of gastric ulcers

Medical intervention is required to heal gastric ulcers and should be done under a veterinarian’s supervision. Nutritional management can be used as an accessory to medical treatment and to prevent gastric ulcers from recurring. The first and most basic nutritional management approach to cure and prevent gastric ulcers in horses is to let a horse be a horse. Access to green grass and free exercise with no or minimal intake of starches and sugars is the best nutritional treatment for gastric ulcers. However, care should be taken that a race horse recently retired from the race track that has not had access to green grass not be given free access to grazing green grass too soon or too quickly – this amounts to a major dietary change and the horse needs to adjust in the same manner any significant change in diet is managed. Free access to good quality hay is very important for normal digestive function and weight management. Research shows that alfalfa hay provides a buffering effect for the stomach and goes a long way towards helping gastric ulcers heal and preventing them from recurring. Triple Crown’s Alfa-Lox™ is a great way to provide alfalfa and nutraceutical ingredients like glutamine and carnitine that work to help gastric and intestinal cells heal and resist ulceration. Other dietary ingredients effective as accessory treatments to healing and preventing gastric ulcers in horses include vegetable oils and fish oils, probiotics, mineral buffers like calcium and magnesium, pectin, and lecithin. This is not a complete list of beneficial ingredients, but it gives you a place to start without wondering if they are for real or just hype.

The easiest way to provide all of these dietary components in one package is to feed Triple Crown Senior. Triple Crown Senior is a beet pulp-based feed containing no grain and a low sugar and starch content. Beet pulp is a great source of pectin; Triple Crown Senior contains 10% fat from vegetable oils, magnesium and calcium, lecithin, prebiotics and probiotics. For horses presenting severe symptoms of gastric ulcers, EquiVision’s ADR and Fish Oil Factor can also be a useful addition to the diet.

Triple Crown Nutrition · 1-800-451-9916 · www.triplecrownfeed.com EquiVision, Inc. · 1-859-873-1220 · www.equivision.com